Ketamine Infusion Therapy for Complex Regional Pain Syndrome (CRPS)

Ketamine Infusion Therapy for Complex Regional Pain Syndrome (CRPS)

By ketamine@dmin | April 25th, 2017 | Categories: Ketamine for Pain, CRPS, Pain Management

Ketamine Infusion Therapy for Pain Management

Complex Regional Pain Syndrome (CRPS) can be a challenging problem due to limited solutions available in conventional medicine to address this condition successfully. But ever since researchers and doctors have started recognizing the benefits of ketamine infusion treatments for patients of CRPS, the treatment success rates have significantly improved.

Dr. Mandell Discusses Ketamine Infusion Therapy for Pain Treatment

Ketamine Clinics of Los Angeles, led by Dr. Steven L Mandel, is one of the dedicated providers of Ketamine Infusion Therapy for a variety of illnesses and pain conditions. Dr. Mandel provides these safe, proven and effective Ketamine Therapy options to patients in Los Angeles, Beverly Hills, California, and surrounding communities.

How does Ketamine Therapy Work on CRPS?

Ketamine Infusion Therapy holds great promise for CRPS patients. While it can be used in several forms, the safest and most effective form of delivery for CRPS patients is the low dose ‘Awake’ version.

A research article on the benefits Ketamine Infusion Therapy published in the Journal of Pain Medicine, said that the basis for using ketamine to treat CRPS may lie in its strong ability to block NMDA receptors. Intense or prolonged pain stimulus leads to the stimulation of NMDA receptors on second-order neurons that produce the phenomena of windup and central sensitization.

Therefore, if NMDA receptors are blocked, it may be possible to block cellular mechanisms supporting windup and central sensitization. Ketamine is the only potent NMDA-blocking drug currently available for clinical use. Controlled ketamine infusion treatments can maintain a level of ketamine in the central nervous system long enough to reverse the effects of the sensitization process and associated pain.

Success of Ketamine for CRPS Patients

Complex Regional Pain Syndrome with Ketamine Infusion TreatmentsOne of the pioneers in Ketamine Infusion Therapy, Dr. Ronald Harbut, worked with the FDA to establish the protocol currently being used for treating CRPS patients with ketamine. The treatment consists of multiple ketamine infusion treatments in low doses under the supervision of a ketamine physician.

Dr. Harbut was asked by the Neurology Today magazine about why the low dose Ketamine Therapy works for many CRPS patients. Dr. Harbut likened Ketamine Therapy to the healing of a broken bone. He said that just as a fractured bone will require time to heal, but it can heal well if a splint is used to the hold the bone steadily in its place for a period of time, and then the splint is taken away.

According to Dr. Harbut, the ketamine treatment does something similar. It provides support and enables the abnormally sensitized nerve cells to heal themselves, so that when ketamine is finally taken away, the pain is reduced or gone.

Ketamine Dose

The patient may typically receive a dose of between 20 mg and 35 mg of ketamine. But the precise dose will depend on the patient’s actual condition of CRPS, their body weight, general health condition, and several other factors.

Patients should take care to choose a specialized clinic that is exclusively dedicated to providing ketamine low dose infusions for conditions such as CRPS. Dr. Mandel receives patients from Los Angeles, Beverly Hills, California, and other cities in this part of the country for ketamine infusion treatments.

For more information about treatments for depression, bipolar, anxiety, post-traumatic stress disorder (PTSD), obsessive compulsive disorder (OCD), fibromyalgia, pain syndromes and other conditions contact us at the Ketamine Clinics of Los Angeles in Southern California (Orange County) by clicking here or calling  310-270-0625 

Treating patients from LA, Beverly Hills, Orange County, San Diego, Palm Springs, San Francisco, Sacramento,CA,  Las Vegas, NV and many other cities from west to east coast.


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